What is the purpose of primase in the process of DNA replication?

Primase plays a crucial role in DNA replication by synthesizing short RNA primers that are necessary for the initiation of DNA synthesis. These primers provide a starting point for DNA polymerases, which cannot begin a new DNA strand on their own without an existing strand to extend. The RNA primers created by primase are complementary to the DNA template strands and are essential for ensuring that DNA replication can proceed in both the leading and lagging strands.

The significance of primase lies in its ability to lay down these primers at specific locations on the template DNA so that DNA polymerases can attach and extend the new DNA strands. This action is pivotal for the overall efficiency and accuracy of DNA replication, allowing for the rapid duplication of the genetic material in preparation for cell division.