In a nonsense mutation, what does the new codon specify?

In a nonsense mutation, the new codon resulting from the mutation specifies a stop codon. This type of mutation occurs when a single nucleotide change in the DNA sequence causes the formation of a codon that signals the termination of protein synthesis before the protein is fully formed.

Normally, codons in the genetic code specify particular amino acids that are linked together to form proteins. However, if a codon is changed to a stop codon due to a mutation, it effectively truncates the protein, potentially leading to a nonfunctional protein product. The premature end of translation can have significant effects on the protein's overall function and stability, and this is particularly important in understanding genetic disorders caused by such mutations.

Thus, this context highlights how a nonsense mutation diverges from the normal codon-to-amino acid translation process, leading to early termination of protein synthesis.